CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 212 enrolled
Drug / intervention
NP Battery +1 morebehavioral
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00528801
NCT00528801N/ACompleted
CompareCT.gov

Neuropsychological Dysfunction and Neuroimaging Abnormalities in Neurologically Intact Adults With Sickle Cell Disease

UCSF Benioff Children's Hospital Oakland·observational·Posted Sep 12, 2007·Updated Mar 21, 2017

In Brief

An observational study evaluating NP Battery and MRI for Anemia, Sickle Cell. Completed, enrolled 212 participants across 12 sites.

Detailed Summary

Sickle cell disease (SCD), also known as sickle cell anemia, is an inherited blood disease that can cause intense pain episodes and may lead to organ failure. Preliminary studies have shown that adults with SCD may have brain abnormalities that contribute to problems with cognitive functioning, including attention and memory difficulties. This study will use brain magnetic resonance imaging (MRI) and neuropsychological testing to examine the differences in cognitive functioning in adults with SCD and adults without SCD. 212 subjects participated in this cross-sectional study consisting of screening questionnaires, a neuropsychological testing battery, and MRI testing. Enrollment into this study ended in May 2008.

Study Details

Study Typeobservational
Allocation--
Masking--
Primary Purpose--
ConditionsAnemia, Sickle Cell
CountriesUnited States
CollaboratorsNational Heart, Lung, and Blood Institute (NHLBI)

Timeline

N/ACompletedFinished
20052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedSep 12, 2007
Enrollment StartDec 1, 2004
Primary CompletionMay 1, 2008
TodayJul 2, 2026
Enrollment to primary: 3.4 yearsPosted 18.8 years ago

Interventions

NP Batterybehavioral

Neuropsych Battery with 7 different tests that evaluate the patients neurological functioning.

MRIprocedure

The MRI is a standard procedure involving 30 minutes under the machine in order to obtain various images of the patients brain.