CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 473 enrolled
Drug / intervention
Zoster Vaccine, Live, (Oka-Merck), ZOSTAVAX™ +2 morebiological
Likely dose
Zoster Vaccine, Live, (Oka-Merck), ZOSTAVAX™ 0.65 mLfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00535730
NCT00535730Phase 3Completed

A Phase III Double-Blind, Randomized, Multicenter Study to Evaluate the Safety, Tolerability, and Immunogenicity of ZOSTAVAX™ Administered Concomitantly Versus Nonconcomitantly With PNEUMOVAX™ 23 in Subjects 60 Years of Age and Older

Merck Sharp & Dohme LLC·interventional·Posted Sep 26, 2007·Updated Apr 12, 2017

In Brief

A Phase 3 clinical trial evaluating Zoster Vaccine, Live, (Oka-Merck), ZOSTAVAX™, Comparator: placebo (concomitant-vaccine matched), and 1 other intervention for Herpes Zoster and Pneumococcal Infection. Completed, enrolled 473 participants.

Detailed Summary

The purpose of this study is to determine whether Zoster Vaccine Live and Pneumococcal Vaccine, polyvalent are as well tolerated and immunogenic when the vaccines are given together (in different body sites), as when they are given alone, in adults 60 years of age and older.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
Countries--
Collaborators--

Timeline

Phase 3CompletedFinished
200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedSep 26, 2007
Enrollment StartJun 1, 2007
Primary CompletionFeb 1, 2008
TodayJul 2, 2026
Enrollment to primary: 8 monthsPosted 18.8 years ago

Interventions

Zoster Vaccine, Live, (Oka-Merck), ZOSTAVAX™biological

0.65 mL injection Zoster Vaccine, Live, (Oka-Merck) over 4 week vaccination period

Comparator: placebo (concomitant-vaccine matched)biological

Pneumococcal Vaccine, Polyvalent (23-valent) 0.5 mL Placebo injection over 4 week vaccination period.

Pneumococcal Vaccine, Polyvalent (23-valent), PNEUMOVAX™ 23biological

Pneumococcal Vaccine, Polyvalent (23-valent) 0.5 mL injection over 4 week vaccination period.