At a glance
ClinicalIndex Comparison RecordPhase 2Completed· 8 enrolled
Drug / intervention
Dexmedetomidine +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
A Phase IV Single Center Cross Over Clinical Study Comparing Two Different Sedations Strategies for Mechanically Ventilated Patients With Neurological Critical Illness
In Brief
A Phase 2 clinical trial evaluating Dexmedetomidine and Propofol for Brain Injury and Intracranial Pressure. Completed, enrolled 8 participants across 1 site.
Detailed Summary
The purpose of this study is to evaluate brain injury when two different drugs (propofol and precedex) are used to sedate patients who need a neurologic exam.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsBrain Injury, Intracranial Pressure
CountriesUnited States
CollaboratorsHospira, now a wholly owned subsidiary of Pfizer
Timeline
Phase 2CompletedFinished
20082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedOct 2007
Enrollment StartJan 2008
Primary CompletionFeb 2008
Study CompletionApr 2010
TodayJul 2026
First PostedOct 2, 2007
Enrollment StartJan 1, 2008
Primary CompletionFeb 1, 2008
Study CompletionApr 1, 2010
TodayJul 2, 2026
Enrollment to primary: 1 monthPosted 18.8 years ago
Interventions
Dexmedetomidinedrug
in this crossover study, subjects will receive 6 hours of propofol and 6 hours of precedex (randomized crossover)
Propofoldrug
in this crossover study, subjects will receive 6 hours of propofol and 6 hours of precedex (randomized crossover)