At a glance
ClinicalIndex Comparison RecordStandardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Prospective Randomized Clinical Trial to Evaluate the Use of Paravertebral Blocks in Reconstructive Breast Surgery
In Brief
A Phase 3 clinical trial evaluating Paravertebral Block, Propofol, and 3 other interventions for Breast Cancer. Completed, enrolled 89 participants across 1 site.
Detailed Summary
Primary Objective: To determine whether the use of a paravertebral block in patients undergoing reconstructive surgery for breast cancer results in decreased immediate post-operative pain compared with patients having only general anesthesia. Secondary Objectives: 1. To determine whether the use of a paravertebral block in patients undergoing reconstructive surgery for breast cancer results in decreased post-operative pain in the first 24 hours after surgery compared with patients having only general anesthesia. 2. To determine whether the use of a paravertebral block in patients undergoing reconstructive surgery for breast cancer results in decreased post-operative nausea and vomiting in the first 24 hours as compared with patients having only general anesthesia. 3. To determine whether the use of a paravertebral block in patients undergoing reconstructive surgery for breast cancer results in a decreased length of hospital stay compared with patients having only general anesthesia.
Study Details
Timeline
Interventions
Paravertebral block given as a bolus injection into the paravertebral space.
2-2.5 mg/kg IV over 1-4 hours during surgery.
50-250 mcg IV over 1-4 hours during surgery.
Ropivacaine given by injection into the paravertebral space along the spinal canal.
0.08 mg/kg IV over 1-4 hours during the surgery.