At a glance
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A Randomized, Double-Blind, Placebo-Controlled Study of Mixed Amphetamine Salts (Adderall-XR) for the Treatment of Adult Attention Deficit Hyperactivity Disorder (ADHD) and Cocaine Dependence
In Brief
A Phase 3 clinical trial evaluating Placebo and Adderall-XR for Adult Attention Deficit Hyperactivity Disorder and Cocaine Dependence. Completed, enrolled 139 participants across 2 sites.
Detailed Summary
The proposed protocol is a 3 group double-blind, placebo-controlled outpatient study of the safety and efficacy of Adderall-XR (ER-MAS) in the treatment of comorbid ADHD and cocaine dependence. Since this medication has independently shown promise in helping with ADHD and cocaine abuse, we are proposing that it may be successful in the treatment of comorbid ADHD and cocaine abuse. We plan to enroll 75 subjects in a 14-week trial. The primary objectives of the study are to determine the efficacy of ER-MAS in promoting cocaine abstinence and improvement in ADHD symptomology among cocaine-dependent patients with comorbid ADHD.
Study Details
Timeline
Interventions
Placebo group
Adderall-XR 60mg/day
Adderall-XR 80mg/day