At a glance
ClinicalIndex Comparison RecordN/ACompleted· 40 enrolled
Drug / intervention
minocycline +1 moredrug
Likely dose
minocycline 200mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Minocycline to Prevent Acute Kidney Injury After Cardiac Surgery
In Brief
A clinical study evaluating minocycline and placebo for Kidney Failure, Acute and Acute Kidney Insufficiency. Completed, enrolled 40 participants across 2 sites.
Detailed Summary
This study proposes to investigate whether treatment with minocycline pre-operatively in patients with mild to moderate chronic kidney disease undergoing cardiac surgery will reduce the occurence of kidney injury.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsKidney Failure, Acute, Acute Kidney Insufficiency
CountriesUnited States
CollaboratorsSatellite Healthcare, Triax Pharmaceuticals
Timeline
N/ACompletedFinished
20082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedNov 2007
Enrollment StartDec 2007
Primary CompletionJul 2011
Study CompletionDec 2013
TodayJul 2026
First PostedNov 12, 2007
Enrollment StartDec 1, 2007
Primary CompletionJul 1, 2011
Study CompletionDec 1, 2013
TodayJul 2, 2026
Enrollment to primary: 3.6 yearsPosted 18.6 years ago
Interventions
minocyclinedrug
given at least for 4 doses (200mg initially then 100mg every 12 hours until surgery)with maximum of 14 doses
placebodrug
placebo will be given for at least 4 doses pre-op to a maximum of 14 doses