At a glance
ClinicalIndex Comparison RecordPhase 2Completed· 210 enrolled
Drug / intervention
Isovue 370, 70 mL +2 moredrug
Likely dose
Isovue 370, 70 mLfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
A Phase II Multicenter Randomized Double Blind Dose Finding Study of Iopamidol Injection 370 in Multidetector Computed Tomographic Angiography (MDCTA) in Patients With Suspected Coronary Artery Stenosis
In Brief
A Phase 2 clinical trial evaluating Isovue 370, 70 mL, Isovue 370, 80 mL, and 1 other intervention for Coronary Artery Disease. Completed, enrolled 210 participants across 1 site.
Detailed Summary
Determine the validity and compare the visualization of arterial segments obtained with 3 doses of iopamidol to determine dose for further investigation in future trials.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsCoronary Artery Disease
CountriesUnited States
Collaborators--
Timeline
Phase 2CompletedFinished
20082009201020112012201320142015201620172018201920202021202220232024202520262027
Enrollment StartNov 2007
First PostedNov 2007
Primary CompletionMay 2010
TodayJul 2026
First PostedNov 15, 2007
Enrollment StartNov 1, 2007
Primary CompletionMay 1, 2010
TodayJul 2, 2026
Enrollment to primary: 2.5 yearsPosted 18.6 years ago
Interventions
Isovue 370, 70 mLdrug
70 mL of iopamidol injection 370 injected at a rate of \>=4 mL/second
Isovue 370, 80 mLdrug
80 mL of iopamidol injection 370 injected at a rate of \>=4 mL/second
Isovue 370, 90 mLdrug
90 mL of iopamidol injection 370 injected at a rate of \>=4 mL/second