CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 16 enrolled
Drug / intervention
18F-fluoromisonidazole +3 moreother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00559377
NCT00559377Phase 2Completed
CompareCT.gov

A Phase 2 Study of Positron Emission Tomography Imaging With [18F]-Fluoromisonidazole (FMISO) and [18F]-Fluorodeoxyglucose (FDG) for Assessment of Tumor Hypoxia in Cervical Cancer

National Cancer Institute (NCI)·interventional·Posted Nov 16, 2007·Updated Dec 30, 2016

In Brief

A Phase 2 clinical trial evaluating 18F-fluoromisonidazole, fluorodeoxyglucose F 18, and 2 other interventions for Cervical Adenocarcinoma and 7 related conditions. Completed, enrolled 16 participants across 1 site.

Detailed Summary

This phase II trial is studying how well PET scans using fluoromisonidazole F 18 and fludeoxyglucose F 18 work in finding oxygen in tumor cells of patients undergoing treatment for newly diagnosed stage 1B, stage II, stage II, or stage IV cervical cancer. Diagnostic procedures using positron emission tomography (PET scan), fluoromisonidazole F 18, and fludeoxyglucose F 18 to find oxygen in tumor cells may help doctors predict how patients will respond to treatment.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsCervical Adenocarcinoma, Cervical Squamous Cell Carcinoma, Stage IB Cervical Cancer, Stage IIA Cervical Cancer, Stage IIB Cervical Cancer, Stage III Cervical Cancer, Stage IVA Cervical Cancer, Stage IVB Cervical Cancer
CountriesUnited States
Collaborators--

Timeline

Phase 2CompletedFinished
20082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedNov 16, 2007
Enrollment StartNov 1, 2007
Primary CompletionJul 1, 2012
Study CompletionMay 1, 2014
TodayJul 2, 2026
Enrollment to primary: 4.7 yearsPosted 18.6 years ago

Interventions

18F-fluoromisonidazoleother

Undergo \^18F FMISO PET scan

fluorodeoxyglucose F 18radiation

Undergo \^18F FDG PET scan

positron emission tomographyprocedure

Undergo \^18F-FMISO and \^18F FDG PET scan

tissue oxygen measurementother

Undergo \^18 F FMISO PET and \^18F FDG PET