CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 260 enrolled
Drug / intervention
AEGR-733 +7 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00559962
NCT00559962Phase 2Completed

A Randomized, Double-blind, Placebo-controlled, Parallel-group Study to Evaluate Low Doses of the MTP-Inhibitor AEGR-733 on Hepatic Fat Accumulation as Measured by Magnetic Resonance Spectroscopy

Aegerion Pharmaceuticals, Inc.·interventional·Posted Nov 19, 2007·Updated Feb 23, 2018

In Brief

A Phase 2 clinical trial evaluating AEGR-733, placebo, and 3 other interventions for Hyperlipidemia. Completed, enrolled 260 participants across 15 sites.

Detailed Summary

To determine safety and effectiveness of low-dose therapeutic AEGR-733 +/- atorvastatin, ezetimibe or fenofibrate (compared to placebo) on liver fat accumulation measured by Magnetic Resonance Spectroscopy

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsHyperlipidemia
CountriesUnited States
Collaborators--

Timeline

Phase 2CompletedFinished
20082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedNov 19, 2007
Enrollment StartOct 1, 2007
Primary CompletionOct 1, 2008
Study CompletionNov 1, 2008
TodayJul 2, 2026
Enrollment to primary: 1 yearPosted 18.6 years ago

Interventions

AEGR-733drug

3 capsules each evening for each 4-week period

placebodrug

3 capsules each evening for each 4-week period

AEGR-733drug

3 capsules each evening for each 4-week period

AEGR-733drug

3 capsules each evening for each 4-week period

AEGR-733drug

3 capsules each evening for each 4-week period

AEGR-733 and atorvastatindrug

3 capsules each evening for each 4-week period

AEGR-733 and fenofibratedrug

3 capsules each evening for each 4-week period

AEGR-733 and ezetimibedrug

3 capsules each evening for each 4-week period