CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 102 enrolled
Drug / intervention
ropivacaine +5 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00562627
NCT00562627Phase 4Completed
CompareCT.gov

Efficacy of Multimodal Peri- and Intraarticular Drug Injections in Total Knee Arthroplasty

Asker & Baerum Hospital·interventional·Posted Nov 22, 2007·Updated Aug 8, 2011

In Brief

A Phase 4 clinical trial evaluating ropivacaine, adrenaline, and 4 other interventions for Osteoarthritis of the Knee. Completed, enrolled 102 participants across 1 site.

Detailed Summary

Total knee arthroplasty (TKA) is associated with moderate to severe postoperative pain, causing patient discomfort, mobilisation and hospital discharge. The aim of this study is to: 1. Compare analgetic efficacy of to types of local infiltration analgesia in total knee arthroplasty. 2. Compare analgetic efficacy of local infiltration analgesia with continuous epidural analgesia.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsOsteoarthritis of the Knee
CountriesNorway
Collaborators--

Timeline

Phase 4CompletedFinished
20082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedNov 22, 2007
Enrollment StartNov 1, 2007
Primary CompletionJun 1, 2009
Study CompletionJul 1, 2009
TodayJul 2, 2026
Enrollment to primary: 1.6 yearsPosted 18.6 years ago

Interventions

ropivacainedrug

intraoperative and 1. postoperative day

adrenalinedrug

intraoperative LIA (IV and IA) and continuous EDA

ketorolacdrug

intraoperative and 1. postoperative day

morphinedrug

intraoperative

fentanyldrug

continuous postoperatively

bupivacainedrug

continuous postoperatively