At a glance
ClinicalIndex Comparison RecordPhase 1Completed· 33 enrolled
Drug / intervention
ibuprofen +1 moredrug
Likely dose
ibuprofen 800 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
A Randomized, Placebo-Controlled Single-Dose 3-Period Crossover Study to Assess the Tolerability and Efficacy of Ibuprofen 800 mg in a Walking Model of Osteoarthritis Pain
In Brief
A Phase 1 clinical trial evaluating ibuprofen and Placebo for Osteoarthritis, Knee. Completed, enrolled 33 participants.
Detailed Summary
The purpose of the study is to see if generic ibuprofen has an effect on osteoarthritis knee pain during a series of timed walks on a treadmill.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsOsteoarthritis, Knee
Countries--
Collaborators--
Timeline
Phase 1CompletedFinished
200720082009201020112012201320142015201620172018201920202021202220232024202520262027
Enrollment StartMar 2007
First PostedNov 2007
Primary CompletionDec 2007
TodayJul 2026
First PostedNov 29, 2007
Enrollment StartMar 1, 2007
Primary CompletionDec 1, 2007
TodayJul 2, 2026
Enrollment to primary: 9 monthsPosted 18.6 years ago
Interventions
ibuprofendrug
Patients will receive 800 mg ibuprofen in one of the three treatment periods.
Placebodrug
Patients will receive placebo to ibuprofen in two of the three treatment periods.