At a glance
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A Pilot Safety and Efficacy Study of Epidural Prefrontal Cortical Stimulation (EpCS) in Severe Treatment Resistant Depression
In Brief
A clinical study evaluating Synergy, Epidural cortical stimulation for Treatment Resistant Depression. Active but no longer recruiting, targeting 5 participants across 1 site.
Detailed Summary
Objective: Chronic epidural cortical stimulation (ECS) involves the neurosurgical placement of an electric wire on the surface of the brain with intermittent activation. Over time, ECS modulates local and distal connected brain regions. It is being currently applied over the motor cortex to treat intractable pain. Because of the important role played by the medial prefrontal cortex in mood regulation, the goal of this study is to apply this minimally invasive neurostimulation modality over medial prefrontal cortex in severely ill depressed subjects who have failed all other attempts at treatment.
Study Details
Timeline
Interventions
Epidural cortical stimulation