CI

At a glance

ClinicalIndex Comparison Record
Phase 1Completed· 18 enrolled
Drug / intervention
10 mg MK-0941 DFC (fasted) +3 moredrug
Likely dose
10 mg MK-0941 DFC (fasted)from record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00567112
NCT00567112Phase 1Completed
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An Open-Label, Randomized, Partially Fixed-Sequence, 4-Period Crossover Study to Assess the Pharmacokinetics After Administration of the DFC and OCT Formulations and the Food Effect on the OCT Formulation of MK-0941 in Patients With Type 2 Diabetes

Merck Sharp & Dohme LLC·interventional·Posted Dec 4, 2007·Updated Mar 23, 2015

In Brief

A Phase 1 clinical trial evaluating 10 mg MK-0941 DFC (fasted), 10 mg MK-0941 OCT (after meal), and 2 other interventions for Type 2 Diabetes Mellitus. Completed, enrolled 18 participants.

Detailed Summary

A study to compare the pharmacokinetics (PK) of the dry filled capsule (DFC) \& oral compressed tablet (OCT) formulations of MK-0941-009 \& to assess the effect of food on the OCT formulation.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsType 2 Diabetes Mellitus
Countries--
Collaborators--

Timeline

Phase 1CompletedFinished
20082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedDec 4, 2007
Enrollment StartNov 1, 2007
Primary CompletionFeb 1, 2008
Study CompletionApr 1, 2008
TodayJul 2, 2026
Enrollment to primary: 3 monthsPosted 18.6 years ago

Interventions

10 mg MK-0941 DFC (fasted)drug

single dose of 10 mg MK-0941 dry filled capsules (DFC) administered in a fasted state

10 mg MK-0941 OCT (after meal)drug

single dose of 10 mg MK-0941 oral compressed tablet (OCT) administered after consumption of a high-fat meal

10 mg MK-0941 OCT (before meal)drug

single dose of 10 mg MK-0941 oral compressed tablet (OCT) administered before consumption of a standard breakfast

10 mg MK-0941 OCT (fasted)drug

single dose of 10 mg MK-0941 oral compressed tablet (OCT) administered in a fasted state