At a glance
ClinicalIndex Comparison RecordN/ACompleted· 42 enrolled
Drug / intervention
Simvastatin +1 moredrug
Likely dose
Simvastatin 40 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Pre-Operative Statin Therapy Versus Placebo in Human Prostate Cancer
In Brief
A clinical study evaluating Simvastatin and Placebo for Cancer and Prostate Cancer. Completed, enrolled 42 participants across 2 sites.
Detailed Summary
This is a randomized trial comparing the effect of oral simvastatin versus placebo on targets of the mevalonate pathway in men undergoing a prostatectomy as planned management for prostate cancer. Observed tissue effects will be correlated with changes in serum cholesterol and low-density lipoprotein.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsCancer, Prostate Cancer
CountriesUnited States
CollaboratorsOregon Health and Science University
Timeline
N/ACompletedFinished
20082009201020112012201320142015201620172018201920202021202220232024202520262027
Enrollment StartDec 2007
First PostedDec 2007
Primary CompletionApr 2013
Study CompletionApr 2017
TodayJul 2026
First PostedDec 13, 2007
Enrollment StartDec 1, 2007
Primary CompletionApr 1, 2013
Study CompletionApr 30, 2017
TodayJul 2, 2026
Enrollment to primary: 5.3 yearsPosted 18.6 years ago
Interventions
Simvastatindrug
40 mg of simvastatin
Placeboother
placebo