CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 60 enrolled
Drug / intervention
Rate Control +14 moredrug
Likely dose
Rate Control 100mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00578617
NCT00578617N/ACompleted
CompareCT.gov

Catheter Ablation Versus Antiarrhythmic Drug Therapy for Atrial Fibrillation - Pilot Trial

Mayo Clinic·interventional·Posted Dec 21, 2007·Updated Jan 4, 2013

In Brief

A clinical study evaluating Rate Control, Ablation Therapy, and 3 other interventions for Atrial Fibrillation and Arrhythmia. Completed, enrolled 60 participants across 10 sites.

Detailed Summary

The CABANA pilot study is designed to test the hypothesis that the treatment strategy of percutaneous left atrial catheter ablation for the purpose of the elimination of atrial fibrillation (AF) is superior to current state-of-the-art therapy with either rate control or anti-arrhythmic drugs for reducing AF recurrences at 1 year follow-up.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsAtrial Fibrillation, Arrhythmia
CountriesUnited States
CollaboratorsDuke Clinical Research Institute, Abbott Medical Devices

Timeline

N/ACompletedFinished
200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedDec 21, 2007
Enrollment StartSep 1, 2006
Primary CompletionFeb 1, 2009
Study CompletionJun 1, 2010
TodayJul 2, 2026
Enrollment to primary: 2.4 yearsPosted 18.5 years ago

Interventions

Rate Controldrug

Metoprolol 50-100mg

Ablation Therapydevice

Rate Controldrug

Atenolol 50-100mg,

Rate controldrug

Propranolol 40-80mg

Rate controldrug

Acebutolol 200mg

Rate controldrug

Carvedilol 6.25mg

Rate Controldrug

Diltiazem 180-240mg

Rate Controldrug

Verapamil 180-240mg

Rate Controldrug

Digoxin 0.125mg

Rhythm Controldrug

Propafenone 450mg

Rhythm controldrug

Flecainide 200mg

Rhythm controldrug

Sotalol 240mg

Rhythm controldrug

Dofetilide 500mcg

Rhythm controldrug

Amiodarone 200mg

Rhythm controldrug

Quinidine 600-900mg