At a glance
ClinicalIndex Comparison RecordPhase 2Completed· 36 enrolled
Drug / intervention
GnRH +4 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Rapid Hormonal Cycling as Treatment for Patients With Prostate Cancer: The Men's Cycle
In Brief
A Phase 2 clinical trial evaluating GnRH, Ketoconazole, and 3 other interventions for Prostate and 2 related conditions. Completed, enrolled 36 participants across 1 site.
Detailed Summary
Objective: To determine the response to rapid hormonal cycling in patients with non-castrate prostate cancer.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsProstate, Cancer, Hormonal Cycling
CountriesUnited States
Collaborators--
Timeline
Phase 2CompletedFinished
200120022003200420052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
Enrollment StartJul 2001
First PostedJan 2008
Primary CompletionMar 2009
TodayJul 2026
First PostedJan 7, 2008
Enrollment StartJul 1, 2001
Primary CompletionMar 1, 2009
TodayJul 2, 2026
Enrollment to primary: 7.7 yearsPosted 18.5 years ago
Interventions
GnRHdrug
leuprolide and goserelin are gonadotropin-releasing hormone analogues
Ketoconazoledrug
An imidazole antifungal agent. reduces adrenal and testicular androgen production in men
Bicalutamidedrug
A pure nonsteroidal antiandrogen
Testosterone transdermal geldrug
an androgenic anabolic steroid
Estrogen transdermal patchdrug
Estradiol is the primary and most potent estrogen