CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 18 enrolled
Drug / intervention
docetaxel +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00589420
NCT00589420Phase 2Completed

A Phase II Study of Sorafenib in Combination With Docetaxel in Patients With Androgen-Independent Prostate Cancer

Abramson Cancer Center at Penn Medicine·interventional·Posted Jan 9, 2008·Updated Feb 17, 2022

In Brief

A Phase 2 clinical trial evaluating docetaxel and sorafenib tosylate for Prostate Cancer. Completed, enrolled 18 participants across 1 site.

Detailed Summary

RATIONALE: Sorafenib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Drugs used in chemotherapy, such as docetaxel, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving sorafenib together with docetaxel may kill more tumor cells. PURPOSE: This phase II trial is studying giving sorafenib together with docetaxel to see how well it works in treating patients with metastatic androgen-independent prostate cancer.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsProstate Cancer
CountriesUnited States
CollaboratorsSanofi, Bayer

Timeline

Phase 2CompletedFinished
20082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedJan 9, 2008
Enrollment StartJul 27, 2007
Primary CompletionFeb 2, 2010
Study CompletionFeb 2, 2011
TodayJul 2, 2026
Enrollment to primary: 2.5 yearsPosted 18.5 years ago

Interventions

docetaxeldrug

sorafenib tosylatedrug