At a glance
ClinicalIndex Comparison RecordStandardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
A Phase II Study of Proton Radiotherapy With Chemotherapy for Nasopharyngeal Carcinoma
In Brief
A Phase 2 clinical trial evaluating Proton/Photon Radiotherapy, Cisplatin, and 1 other intervention for Nasopharyngeal Carcinoma. Completed, enrolled 25 participants across 2 sites.
Detailed Summary
Photon beam radiation is the standard type of radiation used to treat nasopharyngeal carcinoma. Photon beam radiation enters the body and passes through healthy tissue, encounters the tumor and leaves the body through healthy tissue. Proton beam radiation has been shown to have the same effect on tumors as photon beam radiation but it enters the body, passes through healthy tissue, and encounters the tumor but then stops. This means less healthy tissue is affected by proton beam treatment than by photon beam treatment. The purpose of this study is to determine the effectiveness of proton beam radiation in treating nasopharyngeal cancer and reducing the acute and long-term side effects from the treatment. This study will also test to see if the sparing of the healthy tissue can improve quality of life
Study Details
Timeline
Interventions
Given once a day, five days a week, for seven weeks.
Given intravenously once every three weeks during radiation treatment, then once every four weeks for three cycles.
Given as continuous infusion over 4 days starting on the day cisplatin is received after radiation therapy.