CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 115 enrolled
Drug / intervention
Proton Beam Radiationradiation
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00592592
NCT00592592N/ACompleted

A Phase II Trial of Proton RT for the Treatment of Pediatric Rhabdomyosarcoma

Massachusetts General Hospital·interventional·Posted Jan 14, 2008·Updated Jun 18, 2025

In Brief

A clinical study evaluating Proton Beam Radiation for Rhabdomyosarcoma. Completed, enrolled 115 participants across 3 sites.

Detailed Summary

The main purpose of this study is to see if using proton beam radiation therapy instead of photon beam radiation therapy can reduce side effects from radiation treatment for rhabdomyosarcoma. Photon beam radiation is the standard type of radiation for treating most rhabdomyosarcoma and many other types of cancer. Photon beam radiation enters the body and passes through healthy tissue, encounters the tumor, then leaves the body through healthy tissue. A beam of proton radiation enters the body and passes through healthy tissue, encounters tumor, but then stops. This means that less healthy tissue is affected by proton beam radiation than by photon beam radiation.

Study Details

Timeline

N/ACompletedFinished
20052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedJan 14, 2008
Enrollment StartOct 1, 2004
Primary CompletionAug 1, 2010
TodayJul 2, 2026
Enrollment to primary: 5.8 yearsPosted 18.5 years ago

Interventions

Proton Beam Radiationradiation

Once per day, 5 days a week for a total of 4 to 6 weeks.