CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 10 enrolled
Drug / intervention
Hydrochlorothiazide +1 moredrug
Likely dose
Hydrochlorothiazide 25 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00605202
NCT00605202Phase 4Completed
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Effect of Licorice and Hydrochlorothiazide on Plasma Potassium

University of Oulu·interventional·Posted Jan 30, 2008·Updated Dec 15, 2009

In Brief

A Phase 4 clinical trial evaluating Hydrochlorothiazide and Licorice for Hypokalemia. Completed, enrolled 10 participants across 1 site.

Detailed Summary

This clinical trial is designed to study the effect of the combination of licorice and hydrochlorothiazide on plasma potassium levels in volunteers. In one arm, 10 healthy volunteers will be given 32 grams of licorice a day together with a 25 mg dose of daily hydrochlorothiazide for 14 days. This combination is compared with 32 grams of licorice a day for 14 days given in the other arm. The study is a randomized, open-label cross-over trial. There is at least a 3-week wash-out between the arms. The hypothesis is that the combination of licorice and hydrochlorothiazide will cause hypokalemia. The main outcome measure is the change in the plasma level of potassium between the arms.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsHypokalemia
CountriesFinland
Collaborators--

Timeline

Phase 4CompletedFinished
20082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedJan 30, 2008
Enrollment StartFeb 1, 2008
Primary CompletionJan 1, 2009
TodayJul 2, 2026
Enrollment to primary: 11 monthsPosted 18.4 years ago

Interventions

Hydrochlorothiazidedrug

Hydrochlorothiazide 25 mg a day for 14 days.

Licoricedietary

Licorice candy 32 grams a day for 14 days.