CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 89 enrolled
Drug / intervention
perillyl alcohol +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00608634
NCT00608634Phase 2Completed
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Phase 2a Randomized, Placebo-Controlled, Double-Blind Trial of Topical Perillyl Alcohol in Sun Damaged Skin

University of Arizona·interventional·Posted Feb 6, 2008·Updated Apr 1, 2015

In Brief

A Phase 2 clinical trial evaluating perillyl alcohol and placebo for Precancerous Condition. Completed, enrolled 89 participants across 1 site.

Detailed Summary

RATIONALE: Drugs used in chemotherapy, such as perillyl alcohol, work in different ways to stop the growth of abnormal cells, either by killing the cells or by stopping them from dividing. It is not yet known which dose of topical perillyl alcohol is more effective in stopping the development of cancer in sun damaged skin. PURPOSE: This randomized phase II trial is studying high-dose topical perillyl alcohol to see how well it works compared with low-dose topical perillyl alcohol in treating patients with sun damaged skin and actinic keratoses.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsPrecancerous Condition
CountriesUnited States
CollaboratorsNational Cancer Institute (NCI), Arizona Disease Control Research Commission

Timeline

Phase 2CompletedFinished
200420052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedFeb 6, 2008
Enrollment StartMay 1, 2004
Primary CompletionJun 1, 2008
Study CompletionJun 1, 2009
TodayJul 2, 2026
Enrollment to primary: 4.1 yearsPosted 18.4 years ago

Interventions

perillyl alcoholdrug

Applied as topical cream

placeboother

Applied as topical cream