At a glance
ClinicalIndex Comparison RecordN/ACompleted· 420 enrolled
Drug / intervention
Nasal CPAP +1 moreother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Comparison of Humidified High Flow Nasal Cannula to Nasal Continuous Positive Airway Pressure for Non-Invasive Respiratory Support in Neonates
In Brief
A clinical study evaluating Nasal CPAP and Humidified High Flow Nasal Cannula (HHFNC) for Respiratory Insufficiency. Completed, enrolled 420 participants across 9 sites in 2 countries.
Detailed Summary
We hypothesize that the success rate for keeping babies extubated (without a breathing tube for assisted mechanical ventilation), defined as the proportion of infants remaining extubated for a minimum of 72 hours, will be equivalent among infants managed with nasal CPAP compared to humidified high flow nasal cannula (HHFNC).
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsRespiratory Insufficiency
CountriesChina, United States
CollaboratorsIntermountain Health Care, Inc.
Timeline
N/ACompletedFinished
20082009201020112012201320142015201620172018201920202021202220232024202520262027
Enrollment StartDec 2007
First PostedFeb 2008
Primary CompletionMar 2012
Study CompletionJun 2012
TodayJul 2026
First PostedFeb 7, 2008
Enrollment StartDec 1, 2007
Primary CompletionMar 1, 2012
Study CompletionJun 1, 2012
TodayJul 2, 2026
Enrollment to primary: 4.3 yearsPosted 18.4 years ago
Interventions
Nasal CPAPother
Infants randomized to the Standard nasal CPAP via "bubble" or ventilator support at levels of 4-8 cm H2O post extubation
Humidified High Flow Nasal Cannula (HHFNC)other
HHFNC