CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 512 enrolled
Drug / intervention
Chlorhexidine gluconate +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00610324
NCT00610324Phase 4Completed
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Effect of Oral Decontamination Using Chlorhexidine or Potassium Permanganate in ICU Patients: an Open-Labelled Randomized Controlled Trial

King Edward Memorial Hospital·interventional·Posted Feb 7, 2008·Updated Feb 7, 2008

In Brief

A Phase 4 clinical trial evaluating Chlorhexidine gluconate and Potassium permanganate for Nosocomial Pneumonia and 3 related conditions. Completed, enrolled 512 participants across 1 site.

Detailed Summary

Oropharyngeal bacteria play an important role in the pathogenesis of nosocomial pneumonia in critically ill patients. Oral cleansing with chlorhexidine has been shown to decrease incidence of pneumonia in patients undergoing open heart surgery. Its role in critically ill general ICU patients is not yet proven. The present study proposes to study the effectiveness of twice-daily oral cleansing with 0.2% chlorhexidine solution on the incidence of nosocomial pneumonia in ICU patients admitted to a single intensive care unit of an Indian public hospital

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsNosocomial Pneumonia, Healthcare-Associated Pneumonia, Aspiration Pneumonia, Ventilator-Associated Pneumonia
CountriesIndia
Collaborators--

Timeline

Phase 4CompletedFinished
200420052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedFeb 7, 2008
Enrollment StartMay 1, 2004
Primary CompletionOct 1, 2007
Study CompletionDec 1, 2007
TodayJul 2, 2026
Enrollment to primary: 3.4 yearsPosted 18.4 years ago

Interventions

Chlorhexidine gluconatedrug

Twice-daily oropharyngeal cleansing with 0.2% Chlorhexidine gluconate

Potassium permanganatedrug

Twice-daily oropharyngeal cleansing with 0.01% Potassium permanganate