CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 35 enrolled
Drug / intervention
etoposide +8 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00618813
NCT00618813N/ACompleted

A Pilot Study of Chemotherapy Intensification by Adding Vincristine, Topotecan and Cyclophosphamide to Standard Chemotherapy Agents With an Interval Compression Schedule in Newly Diagnosed Patients With Localized Ewing Sarcoma Family of Tumors

Children's Oncology Group·interventional·Posted Feb 20, 2008·Updated Sep 25, 2014

In Brief

A clinical study evaluating radiation therapy, therapeutic conventional surgery, and 7 other interventions for Ewing Sarcoma of Bone and Localized Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor. Completed, enrolled 35 participants across 1 site.

Detailed Summary

This clinical trial is studying the side effects of combination chemotherapy and to see how well they work in treating patients with newly diagnosed localized Ewing sarcoma family of tumors. Drugs used in chemotherapy work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving more than one drug (combination chemotherapy) and giving the drugs in different ways may kill more tumor cells.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States

Timeline

N/ACompletedFinished
20082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedFeb 20, 2008
Enrollment StartMar 1, 2008
Primary CompletionMar 1, 2010
TodayJul 2, 2026
Enrollment to primary: 2 yearsPosted 18.4 years ago

Interventions

radiation therapyother

Undergo radiation therapy

therapeutic conventional surgeryother

Undergo surgery

etoposidedrug

Given IV

ifosfamidedrug

Given IV

doxorubicin hydrochloridedrug

Given IV

cyclophosphamidedrug

Given IV

vincristine sulfatedrug

Given IV

topotecan hydrochloridedrug

Given IV

filgrastimbiological

Given SC