CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 15 enrolled
Drug / intervention
clopidogrel + aspirin +2 moredrug
Likely dose
clopidogrel + aspirin 75mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00619073
NCT00619073N/ACompleted
CompareCT.gov

PACT (Platelet Activity After Clopidogrel Termination)

University of Massachusetts, Worcester·interventional·Posted Feb 20, 2008·Updated May 31, 2018

In Brief

A clinical study evaluating clopidogrel + aspirin, placebo, and 1 other intervention for Blood Platelets and Clopidogrel. Completed, enrolled 15 participants across 1 site.

Detailed Summary

Clopidogrel is a medication that is used to decrease the ability of platelets to form blood clots. The theory has been proposed that, in patients with coronary artery disease or stroke, increased platelet function after discontinuation of clopidogrel therapy is associated with an increased clotting risk. However, this theory has never been rigorously tested. The goal of this research is to determine whether discontinuation of clopidogrel results in increased platelet function.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsBlood Platelets, Clopidogrel
CountriesUnited States
CollaboratorsSanofi, Bristol-Myers Squibb

Timeline

N/ACompletedFinished
20082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedFeb 20, 2008
Enrollment StartApr 1, 2008
Primary CompletionMay 1, 2009
TodayJul 2, 2026
Enrollment to primary: 1.1 yearsPosted 18.4 years ago

Interventions

clopidogrel + aspirindrug

Clopidogrel 75mg plus aspirin 81mg, tablet by mouth daily for 14 days.

placebodrug

Placebo plus aspirin 81 mg, tablet by mouth daily for 14 days.

Aspirindrug

Aspirin 81mg tablet by mouth continued daily alone for 43 days after day 14.