CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 81 enrolled
Drug / intervention
Hyperbaric Oxygendrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00623142
NCT00623142Phase 2Completed
CompareCT.gov

The Effects of Hyperbaric Oxygen Preconditioning On Cardiovascular Protection & Ischemic Reperfusion Injury

Hull University Teaching Hospitals NHS Trust·interventional·Posted Feb 25, 2008·Updated Jul 15, 2019

In Brief

A Phase 2 clinical trial evaluating Hyperbaric Oxygen for Myocardial Reperfusion Injury and Cytoprotection. Completed, enrolled 81 participants across 1 site.

Detailed Summary

The purpose of this study was to determine if treating patients who have coronary heart disease with hyperbaric oxygen (HBO) prior to coronary artery bypass graft (CABG) surgery reduces injury to the heart and vascular system during and after surgery. Furthermore, this study also aims to identify some of the post CABG clinical effects of HBO treatment prior to CABG.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsMyocardial Reperfusion Injury, Cytoprotection
CountriesUnited Kingdom
CollaboratorsNorth of England Medical & Hyperbaric Services

Timeline

Phase 2CompletedFinished
20052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedFeb 25, 2008
Enrollment StartJan 1, 2005
Primary CompletionJan 1, 2007
Study CompletionJan 1, 2008
TodayJul 2, 2026
Enrollment to primary: 2 yearsPosted 18.4 years ago

Interventions

Hyperbaric Oxygendrug

100% Oxygen at 2.4 ATA for 30 minutes followed by 5 minutes break followed by 100% Oxygen at 2.4 ATA for another 30 minutes. This intervention was given about 4 to 5 hours prior to CABG