CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 348 enrolled
Drug / intervention
carvedilol controlled release/lisinopril +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00624065
NCT00624065Phase 3Completed
CompareCT.gov

COR111096, A Randomized, Double-Blind, Active-Controlled, Parallel Group, Multicenter Study Comparing the Proportion of Subjects With Stage 1 or 2 Essential Hypertension Who Achieve Target Blood Pressure While Receiving Either Carvedilol CR + Lisinopril or Lisinopril Monotherapy

GlaxoSmithKline·interventional·Posted Feb 26, 2008·Updated Dec 28, 2016

In Brief

A Phase 3 clinical trial evaluating carvedilol controlled release/lisinopril and lisinopril + placebo for Hypertension. Completed, enrolled 348 participants across 76 sites.

Detailed Summary

Randomized, double-blind, parallel group, multicenter study of subjects with Stage 1 or 2 essential hypertension who are not at target blood pressure (\<140/90mmHg) at Baseline. Subjects will be randomized to receive either carvedilol CR + lisinopril or lisinopril + placebo. Subjects will be uptitrated over a 6 week period until target blood pressure (\<140/90mmHg) is met. The primary objective of the study is to compare the proportion of subjects who achieve target blood pressure after 6 weeks of treatment.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsHypertension
CountriesUnited States
Collaborators--

Timeline

Phase 3CompletedFinished
20082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedFeb 26, 2008
Enrollment StartMar 1, 2008
Primary CompletionAug 1, 2008
TodayJul 2, 2026
Enrollment to primary: 5 monthsPosted 18.3 years ago

Interventions

carvedilol controlled release/lisinoprildrug

carvedilol CR + lisinopril given as separate pills

lisinopril + placebodrug

lisinopril plus placebo to match carvedilol CR