At a glance
ClinicalIndex Comparison RecordEarly Ph 1Completed· 87 enrolled
Drug / intervention
Nicotine +3 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Nicotine Patch Pre-treatment for Smoking Cessation in PTSD
In Brief
A Early Phase 1 clinical trial evaluating Nicotine, Cognitive Behavioral Therapy for Smoking Cessation, and 2 other interventions for Stress Disorders, Posttraumatic and Tobacco Use Disorder. Completed, enrolled 87 participants across 1 site.
Detailed Summary
This study seeks to evaluate the relationship between PTSD, abstinence, and factors associated with relapse in the context of a randomized, clinical smoking cessation trial.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--
Timeline
Early Ph 1CompletedFinished
20082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedFeb 2008
Enrollment StartMay 2008
Primary CompletionMar 2013
TodayJul 2026
First PostedFeb 28, 2008
Enrollment StartMay 1, 2008
Primary CompletionMar 1, 2013
TodayJul 2, 2026
Enrollment to primary: 4.8 yearsPosted 18.3 years ago
Interventions
Nicotinedrug
Delivered through transdermal nicotine patch
Cognitive Behavioral Therapy for Smoking Cessationbehavioral
Manualized protocol for CBT in smoking cessation
Bupropion Sustained Release (SR)drug
Antidepressant
Placebo patchdrug
Pre-treatment placebo transdermal patch