CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 447 enrolled
Drug / intervention
endovascular coil embolizationprocedure
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00626912
NCT00626912Phase 4Completed
CompareCT.gov

PRET: Patients Prone to Recurrence After Endovascular Treatment. A Randomized Trial Comparing Platinum and Hydrogel-coated Coils

Centre hospitalier de l'Université de Montréal (CHUM)·interventional·Posted Feb 29, 2008·Updated Mar 26, 2019

In Brief

A Phase 4 clinical trial evaluating endovascular coil embolization for Intracranial Aneurysm and Subarachnoid Hemorrhage. Completed, enrolled 447 participants across 32 sites in 6 countries.

Detailed Summary

The PRET study aims at comparing two types of coils used in the endovascular treatment of intracranial aneurysms. The first type made of platinum has been used for more than 15 years. The other, referred to as hydrocoil, containing in addition to platinum a polymer layer that expands when in contact with blood, has been in use since 2002. The hypothesis of the PRET study is that the newer hydrocoil will be more effective and yet as safe as the older platinum coil.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsIntracranial Aneurysm, Subarachnoid Hemorrhage
CountriesCanada, Chile, France, Japan, United Kingdom, United States
Collaborators--

Timeline

Phase 4CompletedFinished
200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedFeb 29, 2008
Enrollment StartJun 1, 2007
Primary CompletionOct 1, 2015
Study CompletionDec 1, 2015
TodayJul 2, 2026
Enrollment to primary: 8.3 yearsPosted 18.3 years ago

Interventions

endovascular coil embolizationprocedure

standard endovascular coil embolization with or without adjunct techniques