CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 76 enrolled
Drug / intervention
Amantadinedrug
Likely dose
Amantadine 100 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00627250
NCT00627250N/ACompleted
CompareCT.gov

Utility of Amantadine Hydrochloride in the Treatment of Post-traumatic Irritability: A Randomized, Double-Blind, Placebo-Controlled Trial

Wake Forest University Health Sciences·interventional·Posted Feb 29, 2008·Updated Apr 25, 2022

In Brief

A clinical study evaluating Amantadine for Irritable Mood and 2 related conditions. Completed, enrolled 76 participants.

Detailed Summary

The purpose of this study is to determine if amantadine hydrochloride given 100 mg in the morning and at noon is safe and effective in the treatment of mood and behavior changes (i.e. irritability) after sustaining traumatic brain injury.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsIrritable Mood, Aggression, Traumatic Brain Injury
Countries--
CollaboratorsU.S. Department of Education

Timeline

N/ACompletedFinished
2003200420052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedFeb 29, 2008
Enrollment StartMar 1, 2003
Primary CompletionNov 1, 2007
TodayJul 2, 2026
Enrollment to primary: 4.7 yearsPosted 18.3 years ago

Interventions

Amantadinedrug

Amantadine 100 mg every morning and 12 noon