CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 41 enrolled
Drug / intervention
AtraumaticTeeth Extraction +3 moreprocedure
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00641316
NCT00641316N/ACompleted

A Prospective Study of Bone Augmentation Techniques in Extraction Sockets and Implant Surface Textures

University of Alabama at Birmingham·interventional·Posted Mar 24, 2008·Updated Jul 19, 2024

In Brief

A clinical study evaluating AtraumaticTeeth Extraction and Atraumatic Teeth Extraction/Grafted Extraction Sockets for Unrestorable Dentition and Post-Extraction Sockets. Completed, enrolled 41 participants across 1 site.

Detailed Summary

When a tooth is extracted the ridge of bone that held the tooth in place begins to heal and over time new bone grows to fill the empty space left by the missing tooth. Sometimes this process works very well and new bone grows to completely fill the socket, at other times new bone fails to fill in the space completely and patients are left with uneven bone-fill. Grafted extraction sockets may fill with bone faster and more evenly than those without grafts, allowing the dentist to have greater control over the healing process and to repair the area with dental implants in a shorter period of time. This study will help determine if grafting an extraction socket, with or without enriching the graft material, is an added benefit when compared to allowing the socket to heal naturally. The study will also assess how well two different dental implant designs used to restore the area will function over time.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
CollaboratorsBioHorizons, Inc.

Timeline

N/ACompletedFinished
20082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedMar 24, 2008
Enrollment StartApr 1, 2008
Primary CompletionApr 1, 2010
Study CompletionNov 1, 2012
TodayJul 2, 2026
Enrollment to primary: 2 yearsPosted 18.3 years ago

Interventions

AtraumaticTeeth Extractionprocedure

Teeth extraction alone, allowed to heal for 2 months followed by implant therapy to the sites

Atraumatic Teeth Extraction/Grafted Extraction Socketsprocedure

Teeth extraction/post-extraction socket grafting with Freeze-Dried Bone Allograft (FDBA) mixed with Tri-Calcium Phosphate(TCP) allowed to heal for 2 months followed by dental implant therapy to the sites

Atraumatic Teeth Extraction/Grafted Extraction Socketsprocedure

Teeth extraction/post-extraction socket grafting with FDBA/TCP enriched with Autologous Platelet-Rich Plasma (PRP) allowed to heal for 2 months followed by dental implant therapy to the sites

Atraumatic Teeth Extraction/Grafted Extraction Socketsprocedure

Teeth extraction/post-extraction socket grafting with FDBA/TCP enriched with Platelet-Derived Growth Factors (PDGF) allowed to heal for 2 months followed by dental implant therapy to the sites