CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 378 enrolled
Drug / intervention
Meningococcal Polysaccharide Diphtheria Protein Conjugate (Menactra®) +5 morebiological
Likely dose
Meningococcal Polysaccharide Diphtheria Protein Conjugate (Menactra®) 0.5 mLfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00643916
NCT00643916Phase 2Completed

Safety and Immunogenicity of a Tetravalent (A, C, Y, and W-135) Meningococcal Diphtheria Toxoid Conjugate Vaccine (TetraMenD) In Toddlers 9 to 18 Months of Age

Sanofi Pasteur, a Sanofi Company·interventional·Posted Mar 26, 2008·Updated Feb 14, 2014

In Brief

A Phase 2 clinical trial evaluating Meningococcal Polysaccharide Diphtheria Protein Conjugate (Menactra®) and A/C/Y/W-135, Meningococcal Polysaccharide Vaccine (Menomune®) for Meningitis and Meningococcal Infection. Completed, enrolled 378 participants across 14 sites.

Detailed Summary

The purpose of this clinical trial is to describe the safety and immunogenicity of one or two doses of Menactra® (TetraMenD) administered in children less than 2 years of age. Primary Objective: To describe the immunogenicity profile of one or two doses of Menactra® (TetraMenD) when administered to subjects aged 9, 12, 15, or 18 months in comparison to the immunogenicity of one dose of Menomune® when administered to children aged 3 years to \<6 years of age.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

Phase 2CompletedFinished
20052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedMar 26, 2008
Enrollment StartDec 1, 2004
Primary CompletionMar 1, 2006
Study CompletionOct 1, 2007
TodayJul 2, 2026
Enrollment to primary: 1.3 yearsPosted 18.3 years ago

Interventions

Meningococcal Polysaccharide Diphtheria Protein Conjugate (Menactra®)biological

0.5 mL, Intramuscular (at age 9 and 12 months)

Meningococcal Polysaccharide Diphtheria Protein Conjugate (Menactra®)biological

0.5 mL, Intramuscular (at age 9 and 15 months)

Meningococcal Polysaccharide Diphtheria Protein Conjugate (Menactra®)biological

0.5 mL, Intramuscular (at age 12 and 15 months)

Meningococcal Polysaccharide Diphtheria Protein Conjugate (Menactra®)biological

0.5 mL, Intramuscular (at age 15 months)

Meningococcal Polysaccharide Diphtheria Protein Conjugate (Menactra®)biological

0.5 mL, Intramuscular (at age 18 months)

A/C/Y/W-135, Meningococcal Polysaccharide Vaccine (Menomune®)biological

0.5 mL, Subcutaneous (at 3 years to \<6 years of age)