CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 14 enrolled
Drug / intervention
Gadolinium +5 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00660543
NCT00660543N/ACompleted
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Early Assessment of Tumor Response to Therapy Using Ferumoxytol (Code 7228) as an MR Contrast Agent in Patients With Glioblastoma Multiforme (MedDRA Code 10018337)

OHSU Knight Cancer Institute·interventional·Posted Apr 17, 2008·Updated May 16, 2017

In Brief

A clinical study evaluating Gadolinium, Ferumoxytol Non-Stoichiometric Magnetite, and 4 other interventions for Adult Brain Glioblastoma. Completed, enrolled 14 participants across 1 site.

Detailed Summary

This pilot clinical trial studies how a magnetic resonance imaging (MRI) study with ferumoxytol works as a contrasting agent in assessing early response in patients with glioblastoma multiforme receiving temozolomide and radiation therapy. Ferumoxytol is a very small form of iron particles that are injected into the body and taken up by certain tissues which may make these tissues easier to see during imaging. Diagnostic procedures, such as an MRI study with ferumoxytol, may help measure a patient's response to earlier treatment.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsAdult Brain Glioblastoma
CountriesUnited States
CollaboratorsNational Cancer Institute (NCI)

Timeline

N/ACompletedFinished
200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedApr 17, 2008
Enrollment StartDec 1, 2006
Primary CompletionJun 1, 2014
TodayJul 2, 2026
Enrollment to primary: 7.5 yearsPosted 18.2 years ago

Interventions

Gadoliniumdrug

Given IV

Ferumoxytol Non-Stoichiometric Magnetitedrug

Given IV

Dynamic Contrast-Enhanced Magnetic Resonance Imagingother

Undergo DCE MRI

Dynamic Susceptibility Contrast-Enhanced Magnetic Resonance Imagingother

Undergo DSC MRI

Diffusion Weighted Imagingother

Undergo DWI

MRI-Based Angiogramother

Undergo TOF MR angiography