CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 99 enrolled
Drug / intervention
DHEA +3 moredietary
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00664053
NCT00664053Phase 4Completed
CompareCT.gov

Effects of DHEA/Exercise on Bone, Muscle and Balance

National Aeronautics and Space Administration (NASA)·interventional·Posted Apr 22, 2008·Updated Apr 29, 2008

In Brief

A Phase 4 clinical trial evaluating DHEA, Yoga, and 2 other interventions for Osteoporosis and Frailty. Completed, enrolled 99 participants across 1 site.

Detailed Summary

The purpose of this study is to examine whether muscle strength and balance will improve in women with frailty selected for dehydroepiandrosterone sulfate (DHEAS) levels below 550 ng/dl treated with DHEAS supplementation and Hatha yoga. Investigators believe the effects of both treatments will improve outcomes more than either treatment alone and may be additive; in addition, lean body mass, skeletal muscle mass, markers of bone turnover and physical performance will improve following treatment with DHEA and/or yoga.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsOsteoporosis, Frailty
CountriesUnited States
CollaboratorsUniversity of Connecticut

Timeline

Phase 4CompletedFinished
20052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedApr 22, 2008
Enrollment StartOct 1, 2004
Primary CompletionOct 1, 2006
TodayJul 2, 2026
Enrollment to primary: 2 yearsPosted 18.2 years ago

Interventions

DHEAdietary

50mg daily for 6 months

Yogabehavioral

2 sessions per week for 6 months

Placebodietary

Placebo supplement every day for 6 months

Aerobicsbehavioral

Walking/chair aerobics program 2 sessions per week for 6 months