CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 219 enrolled
Drug / intervention
Fostamatinib disodium (R935788) +1 moredrug
Likely dose
Fostamatinib disodium (R935788) 100 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00665626
NCT00665626Phase 2Completed

A Phase II, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel Dose Study of R935788 in Patients With Rheumatoid Arthritis Who Have Failed at Least One Biologic

Rigel Pharmaceuticals·interventional·Posted Apr 24, 2008·Updated May 1, 2017

In Brief

A Phase 2 clinical trial evaluating Fostamatinib disodium (R935788) and Placebo for Rheumatoid Arthritis. Completed, enrolled 219 participants across 44 sites in 7 countries.

Detailed Summary

The purpose of this study is to determine whether the Spleen Tyrosine Kinase (Syk) Inhibitor, R935788 (R788) at a dose of 100 mg, tablet, orally, twice-a-day is effective in the treatment of Rheumatoid Arthritis in patients who have 'failed' a biologic therapy.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesBelgium, Colombia, France, Germany, Italy, Peru, United States
Collaborators--

Timeline

Phase 2CompletedFinished
20082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedApr 24, 2008
Enrollment StartMay 1, 2008
Primary CompletionJun 1, 2009
TodayJul 2, 2026
Enrollment to primary: 1.1 yearsPosted 18.2 years ago

Interventions

Fostamatinib disodium (R935788)drug

R935788 100 mg tablet, orally, twice-a-day

Placebodrug

Placebo, orally, twice-a-day