CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 709 enrolled
Drug / intervention
melatonin +1 moredietary
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00668707
NCT00668707Phase 3Completed

Adjuvant Melatonin for Prevention of Lung Cancer Recurrence and Mortality: A Randomized Placebo Controlled Clinical Trial

The Canadian College of Naturopathic Medicine·interventional·Posted Apr 29, 2008·Updated Aug 3, 2021

In Brief

A Phase 3 clinical trial evaluating melatonin and placebo for Non Small Cell Lung Cancer. Completed, enrolled 709 participants across 8 sites.

Detailed Summary

There is evidence to support the use of melatonin, a natural health product, as an additional treatment aid for cancer patients. This study is designed to see if the daily ingestion of 20 milligrams of melatonin for one year can lower the incidence of developing lung cancer recurrence and/or death. Only patients with a diagnosis of non small cell lung cancer who are eligible for surgical resection can participate in the trial. The study will also be assessing for changes in quality of life, pain, fatigue, anxiety, sleep, and depression amongst the participants.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesCanada

Timeline

Phase 3CompletedFinished
20082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedApr 29, 2008
Enrollment StartSep 1, 2007
Primary CompletionMar 9, 2017
Study CompletionNov 30, 2017
TodayJul 2, 2026
Enrollment to primary: 9.5 yearsPosted 18.2 years ago

Interventions

melatonindietary

20 mgs ingested nightly

placebodietary

similar to experimental in all ways except for lack of active ingredient