CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 177 enrolled
Drug / intervention
Placebo +2 moredrug
Likely dose
Sativex® 27 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00674609
NCT00674609Phase 3Completed

A Double Blind, Randomized, Parallel Group, Placebo Controlled, Comparative Study of the Efficacy, Safety and Tolerability of Cannabis Based Medicine (CBM) Extracts in Patients With Cancer-related Pain.

Jazz Pharmaceuticals·interventional·Posted May 8, 2008·Updated May 3, 2023

In Brief

A Phase 3 clinical trial evaluating Placebo, Sativex®, and 1 other intervention for Palliative Care and 2 related conditions. Completed, enrolled 177 participants across 1 site.

Detailed Summary

The purpose of this study is to determine whether Sativex® and GW-2000-02 are effective in the management of subjects with intractable cancer-related pain.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited Kingdom
Collaborators--

Timeline

Phase 3CompletedFinished
20022003200420052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedMay 8, 2008
Enrollment StartFeb 1, 2002
Primary CompletionFeb 1, 2004
Study CompletionMar 1, 2004
TodayJul 2, 2026
Enrollment to primary: 2 yearsPosted 18.2 years ago

Interventions

Placebodrug

Containing colourants and excipients. Subjects received study medication delivered in 100 µl actuations by a pump action oromucosal spray. Maximum permitted dose was eight actuations in any three hour period and 48 actuations in 24 hours.

Sativex®drug

Containing D9 tetrahydrocannabinol (THC), 27 mg/ml: cannabidiol (CBD), 25 mg/ml. Subjects received study medication delivered in 100 µl actuations by a pump action oromucosal spray. Maximum permitted dose was eight actuations in any three hour period and 48 actuations (THC 130 mg:CBD 120 mg) in 24 hours.

THC Alonedrug

Containing THC, 27 mg/ml, as extract of Cannabis sativa L. Subjects received study medication delivered in 100 µl actuations by a pump action oromucosal spray. Maximum permitted dose was eight actuations in any three hour period and 48 actuations (THC 130 mg) in 24 hours.