CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 18 enrolled
Drug / intervention
Simvastatin +1 moredrug
Likely dose
Simvastatin 40mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00676897
NCT00676897Phase 3Completed
CompareCT.gov

Study of Statin Therapy in the Treatment of Sepsis

Beth Israel Deaconess Medical Center·interventional·Posted May 13, 2008·Updated Jun 14, 2017

In Brief

A Phase 3 clinical trial evaluating Simvastatin and Placebo for Septic Shock. Completed, enrolled 18 participants across 1 site.

Detailed Summary

Simvastatin will attenutat IL-6 levels and lead to a more rapid shock reversal than placebo

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsSeptic Shock
CountriesUnited States
Collaborators--

Timeline

Phase 3CompletedFinished
20082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedMay 13, 2008
Enrollment StartFeb 1, 2008
Primary CompletionDec 1, 2010
TodayJul 2, 2026
Enrollment to primary: 2.8 yearsPosted 18.1 years ago

Interventions

Simvastatindrug

Simvastatin 40mg PO or NGT

Placebodrug

Corn Starch