CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 1,202 enrolled
Drug / intervention
bleomycin sulfate +10 morebiological
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00678327
NCT00678327Phase 3Completed
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A Randomized Phase III Trial to Assess Response Adapted Therapy Using FDG-PET Imaging in Patients With Newly Diagnosed, Advanced Hodgkin Lymphoma

University College, London·interventional·Posted May 15, 2008·Updated May 8, 2024

In Brief

A Phase 3 clinical trial evaluating bleomycin sulfate, filgrastim, and 9 other interventions for Lymphoma. Completed, enrolled 1,202 participants across 1 site.

Detailed Summary

RATIONALE: Imaging procedures, such as fludeoxyglucose F 18 (FDG)-PET/CT scan, done before, during, and after chemotherapy may help doctors assess a patient's response to treatment and help plan the best treatment. It is not yet known whether FDG-PET/CT imaging is effective in assessing response to chemotherapy in patients with newly diagnosed Hodgkin lymphoma. PURPOSE: This randomized phase III trial is studying FDG-PET/CT imaging to see how well it works in assessing response to chemotherapy in patients with newly diagnosed stage II, stage III, or stage IV Hodgkin lymphoma.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsLymphoma
CountriesUnited Kingdom
CollaboratorsCancer Research UK, Cancer Research UK & UCL Cancer Trials Centre

Timeline

Phase 3CompletedFinished
20082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedMay 15, 2008
Enrollment StartAug 29, 2008
Primary CompletionJan 31, 2016
Study CompletionMay 1, 2024
TodayJul 2, 2026
Enrollment to primary: 7.4 yearsPosted 18.1 years ago

Interventions

bleomycin sulfatebiological

Given IV

filgrastimbiological

Given subcutaneously

pegfilgrastimbiological

Given subcutaneously

cyclophosphamidedrug

Given IV

dacarbazinedrug

Given IV

doxorubicin hydrochloridedrug

Given IV

etoposidedrug

Given IV

prednisolonedrug

Given orally

procarbazine hydrochloridedrug

Given orally

vinblastine sulfatedrug

Given IV

vincristine sulfatedrug

Given IV