CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 102 enrolled
Drug / intervention
One-Stage Full-Mouth Disinfection +1 moreprocedure
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00681564
NCT00681564Phase 3Completed
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Impact of Periodontal Therapy on Endothelial Function

Universidad del Valle, Colombia·interventional·Posted May 21, 2008·Updated Apr 17, 2014

In Brief

A Phase 3 clinical trial evaluating One-Stage Full-Mouth Disinfection and Periodontal care for Periodontitis. Completed, enrolled 102 participants across 2 sites.

Detailed Summary

The purpose of this study is to determine the effect of periodontal therapy on endothelial function and other biomarkers of cardiovascular disease

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsPeriodontitis
CountriesColombia
Collaborators--

Timeline

Phase 3CompletedFinished
20082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedMay 21, 2008
Enrollment StartMay 1, 2008
Primary CompletionMar 1, 2011
Study CompletionJan 1, 2012
TodayJul 2, 2026
Enrollment to primary: 2.8 yearsPosted 18.1 years ago

Interventions

One-Stage Full-Mouth Disinfectionprocedure

* Scaling and root planing, four quadrants in one session * Tongue brushing with a 1% chlorhexidine gel (1 minute) * Mouth rinsing with a 0.2% chlorhexidine solution for (2 minutes) * Subgingival chlorhexidine (1%) irrigation in all pockets * Twice daily rinsing with clorhexidine (1 minute) during fourteen days after the periodontal intervention * Basic oral hygiene instructions * Dental extractions will be performed at the end of patient followup (only in cases of teeth that could not be saved)

Periodontal careprocedure

* Basic oral hygiene instructions * Supragingival plaque removal