At a glance
ClinicalIndex Comparison RecordPhase 3Completed· 349 enrolled
Drug / intervention
metoclopramide +3 moredrug
Likely dose
Diphenhydramine 25mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Metoclopramide for Acute Migraine: A Dose Finding Study
In Brief
A Phase 3 clinical trial evaluating metoclopramide and Diphenhydramine 25mg for Migraine. Completed, enrolled 349 participants across 1 site.
Detailed Summary
Metoclopramide is an effective intravenous treatment for acute migraine attacks, but we do not know the best dose to administer. This study compares three different doses of metoclorpamide.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsMigraine
CountriesUnited States
Collaborators--
Timeline
Phase 3CompletedFinished
20082009201020112012201320142015201620172018201920202021202220232024202520262027
Enrollment StartApr 2008
First PostedMay 2008
Primary CompletionMar 2010
TodayJul 2026
First PostedMay 22, 2008
Enrollment StartApr 1, 2008
Primary CompletionMar 1, 2010
TodayJul 2, 2026
Enrollment to primary: 1.9 yearsPosted 18.1 years ago
Interventions
metoclopramidedrug
metoclopramide 20 mg
metoclopramidedrug
metoclopramide 40 mg
metoclopramidedrug
metoclopramide 10 mg
Diphenhydramine 25mgdrug
Diphenhydramine 25mg, administered as an intravenous drip over 20 minutes