CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 60 enrolled
Drug / intervention
Experimental Sequence ABC +5 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00685477
NCT00685477N/ACompleted
CompareCT.gov

Dose Response of Intravenous Sincalide (CCK-8) for Gallbladder Emptying

Temple University·interventional·Posted May 28, 2008·Updated Feb 17, 2017

In Brief

A clinical study evaluating Experimental Sequence ABC, Experimental Sequence ACB, and 4 other interventions for Healthy. Completed, enrolled 60 participants across 1 site.

Detailed Summary

This is a clinical research study to establish normal values for the infusion of a synthetic form of the hormone cholecystokinin(CCK-8) for gallbladder emptying. Cholecystokinin is released from the small bowel to stimulate the pancreas and gallbladder to help digest and absorb food. Some people have gallbladder problems and need to be tested with the synthetic cholecystokinin ( Kinevac®, Bracco Diagnostics, Inc.). The aim of this study is to find out how differing amounts and intravenous infusion times of CCK-8 affect gallbladder emptying. The findings in normal subjects will be used to establish normal values that can then be compared with patients with suspected gallbladder disease.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsHealthy
CountriesUnited States
CollaboratorsJohns Hopkins University, Penn State University, Memorial Health University Medical Center

Timeline

N/ACompletedFinished
20082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedMay 28, 2008
Enrollment StartMay 1, 2008
Primary CompletionMay 1, 2009
Study CompletionJul 1, 2009
TodayJul 2, 2026
Enrollment to primary: 1 yearPosted 18.1 years ago

Interventions

Experimental Sequence ABCdrug

Drug will be given over 15 minutes, followed by infusion over 30 minutes, followed by infusion over 60 minutes

Experimental Sequence ACBdrug

Drug infused over 15 minutes, followed by infusion over 60 minutes, followed by infusion over 30 minutes

Experimental Sequence BACdrug

Drug will be given over 30 min infusion, followed by 15 minute infusion, followed by 60 minute infusion

Experimental Sequence BCAdrug

Drug will be given over 30 min infusion, followed by 60 minute infusion, followed by 15 minute infusion

Experimental Sequence CABdrug

Drug will be given over 60 min infusion, followed by 15 minute infusion, followed by 30 minute infusion

Experimental Sequence CBAdrug

Drug will be given over 60 min infusion, followed by 30 minute infusion, followed by 15 minute infusion