CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 318 enrolled
Drug / intervention
Placebo +5 moredrug
Likely dose
CP-690,550 10mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00687193
NCT00687193Phase 2Completed
CompareCT.gov

A Phase 2, Randomized, Double-Blind, Placebo-Controlled, Multicenter Study To Confirm Dose Responsiveness Following 12 Weeks Of The Administration Of CP-690,550 (5 Doses) Or Placebo In Subjects With Active Rheumatoid Arthritis Inadequately Responding To At Least 1 DMARD

Pfizer·interventional·Posted May 30, 2008·Updated Mar 25, 2013

In Brief

A Phase 2 clinical trial evaluating Placebo and CP-690,550 for Arthritis, Rheumatoid. Completed, enrolled 318 participants across 40 sites.

Detailed Summary

To evaluate the dose-response relationship of 5 dose of CP-690,550, compared to placebo for the treatment of signs and symptoms in patients with active RA who failed an adequate trial of therapy with at least 1 DMARD in a 12-week therapy.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsArthritis, Rheumatoid
CountriesJapan
Collaborators--

Timeline

Phase 2CompletedFinished
20082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedMay 30, 2008
Enrollment StartMar 1, 2009
Primary CompletionJul 1, 2010
TodayJul 2, 2026
Enrollment to primary: 1.3 yearsPosted 18.1 years ago

Interventions

Placebodrug

Placebo BID, 3 blinded tablets administered BID for 12 weeks

CP-690,550drug

10mg BID, 3 blinded tablets administered BID for 12 weeks

CP-690,550drug

15mg BID, 3 blinded tablets administered BID for 12 weeks

CP-690,550drug

1mg BID, 3 blinded tablets administered BID for 12 weeks

CP-690,550drug

3mg BID, 3 blinded tablets administered BID for 12 weeks

CP-690,550drug

5mg BID, 3 blinded tablets administered BID for 12 weeks