At a glance
ClinicalIndex Comparison RecordPhase 2Completed· 108 enrolled
Drug / intervention
Ondansetron +1 moredrug
Likely dose
Ondansetron 4 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
New Medication Treatment for Stimulant Dependence
In Brief
A Phase 2 clinical trial evaluating Ondansetron and Placebo for Cocaine Dependence. Completed, enrolled 108 participants across 2 sites.
Detailed Summary
This study will evaluate the efficacy of ondansetron compared with placebo in the treatment of cocaine dependence.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsCocaine Dependence
CountriesUnited States
CollaboratorsNational Institute on Drug Abuse (NIDA)
Timeline
Phase 2CompletedFinished
20082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedJun 2008
Enrollment StartJul 2008
Primary CompletionDec 2013
TodayJul 2026
First PostedJun 3, 2008
Enrollment StartJul 1, 2008
Primary CompletionDec 1, 2013
TodayJul 2, 2026
Enrollment to primary: 5.4 yearsPosted 18.1 years ago
Interventions
Ondansetrondrug
4 mg twice a day + Cognitive Behavioral Therapy + Brief Behavioral Enhancement Therapy
Placebodrug
twice a day + Cognitive Behavioral Therapy + Brief Behavioral Enhancement Therapy