CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 55 enrolled
Drug / intervention
Metformin 500 mg tabletdrug
Likely dose
Metformin 500 mg tabletfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00703508
NCT00703508N/ACompleted
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Pharmacogenetics of Metformin Action in PCOS

Virginia Commonwealth University·interventional·Posted Jun 23, 2008·Updated Jun 14, 2017

In Brief

A clinical study evaluating Metformin 500 mg tablet for Polycystic Ovary Syndrome. Completed, enrolled 55 participants across 2 sites.

Detailed Summary

1. The polycystic ovary syndrome is the major cause of infertility in the United States. Metformin has been shown to increase frequency of ovulations in PCOS, and is used in clinical practice to treat infertility, but some women with PCOS do not respond to metformin treatment. 2. Knowing that a specific gene predicts the effect of metformin on ovulation would facilitate more efficient and effective treatment of infertility in PCOS.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsPolycystic Ovary Syndrome
CountriesUnited States
CollaboratorsEunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

Timeline

N/ACompletedFinished
20082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedJun 23, 2008
Enrollment StartJul 1, 2008
Primary CompletionSep 1, 2013
Study CompletionMar 1, 2014
TodayJul 2, 2026
Enrollment to primary: 5.2 yearsPosted 18.0 years ago

Interventions

Metformin 500 mg tabletdrug

Metformin 500 mg tablets; two tablets every 12 hours for 9 months