CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 8,094 enrolled
Drug / intervention
Vitamin E +3 moredrug
Likely dose
Vitamin E 400 IUfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00706121
NCT00706121Phase 3Completed
CompareCT.gov

S0000D: A Study of the Effect of Vitamin E and/or Selenium on Adenomatous Colorectal Polyps (ACP) in Participants Enrolled in SELECT

SWOG Cancer Research Network·interventional·Posted Jun 27, 2008·Updated Dec 16, 2019

In Brief

A Phase 3 clinical trial evaluating Vitamin E, Selenium, and 2 other interventions for Colorectal Cancer and Precancerous Condition. Completed, enrolled 8,094 participants across 1 site.

Detailed Summary

RATIONALE: Studying tissue samples in the laboratory from participants receiving treatment on the Selenium and Vitamin E Cancer Prevention Trial (SELECT) SWOG-S0000 may help doctors predict a participant's response to treatment and help plan the best treatment. PURPOSE: This phase III trial is studying the effect of vitamin E and/or selenium on colorectal polyps in men enrolled on SELECT Trial SWOG-S0000.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsColorectal Cancer, Precancerous Condition
CountriesUnited States
CollaboratorsNational Cancer Institute (NCI)

Timeline

Phase 3CompletedFinished
20082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedJun 27, 2008
Enrollment StartJun 1, 2008
Primary CompletionOct 1, 2015
Study CompletionJan 1, 2018
TodayJul 2, 2026
Enrollment to primary: 7.3 yearsPosted 18.0 years ago

Interventions

Vitamin Edrug

400 IU daily by mouth for 7 - 12 years

Seleniumdrug

200 mcg daily for 7 - 12 years

Vitamin E placebodrug

1 pill by mouth daily for 7 - 12 years

selenium placebodrug

1 pill by mouth daily for 7 - 12 years