CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 44 enrolled
Drug / intervention
Minimally Invasive Total Knee Arthroplasty [TKA Min] +1 moreprocedure
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00710840
NCT00710840Phase 2Completed
CompareCT.gov

Functional Outcomes Following Minimally Invasive Total Knee Arthroplasty

University of Colorado, Denver·interventional·Posted Jul 4, 2008·Updated Jun 10, 2015

In Brief

A Phase 2 clinical trial evaluating Minimally Invasive Total Knee Arthroplasty [TKA Min] and Total Knee Arthroplasty (TKA) Traditional for Osteoarthritis. Completed, enrolled 44 participants across 3 sites.

Detailed Summary

Osteoarthritis (OA) is a long-term degenerative joint disease that disables about 10% of people over the age of 60 and compromises the quality of life of more than 20 million Americans. A procedure called total knee arthroplasty (TKA), in which the affected surface of the knee joint is replaced by plastic or metal, has been successful in restoring comfort and mobility to formerly arthritic joints. This study will compare quadriceps muscle strength, knee range of motion, and pain in people who have had a traditional TKA with those who have had a minimally invasive TKA.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsOsteoarthritis
CountriesUnited States
CollaboratorsNational Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

Timeline

Phase 2CompletedFinished
20082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedJul 4, 2008
Enrollment StartJun 1, 2008
Primary CompletionFeb 1, 2011
Study CompletionJan 1, 2012
TodayJul 2, 2026
Enrollment to primary: 2.7 yearsPosted 18.0 years ago

Interventions

Minimally Invasive Total Knee Arthroplasty [TKA Min]procedure

TKA Min is a procedure in which diseased and painful joint surfaces of the knee are replaced by metal and plastic components shaped to allow continued motion of the knee. TKA Min, as opposed to TKA Traditional, employs smaller skin incisions and smaller instrumentation and avoids turning the knee cap out and dislocating the knee. This procedure also avoids disrupting the knee extensor mechanism and the suprapatellar pouch and minimizes extreme knee flexion during surgery.

Total Knee Arthroplasty (TKA) Traditionalprocedure

TKA is a procedure in which diseased and painful joint surfaces of the knee are replaced by metal and plastic components shaped to allow continued motion of the knee.