CI

At a glance

ClinicalIndex Comparison Record
Phase 1Completed· 82 enrolled
Drug / intervention
Mnemonic strategy training (MST) +2 morebehavioral
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00714571
NCT00714571Phase 1Completed
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Behavioral and Neuroimaging Changes After Cognitive Rehab in TBI and MCI

VA Office of Research and Development·interventional·Posted Jul 14, 2008·Updated Jan 4, 2017

In Brief

A Phase 1 clinical trial evaluating Mnemonic strategy training (MST), Repeated exposure (XP), and 1 other intervention for Mild Cognitive Impairment and 2 related conditions. Completed, enrolled 82 participants across 1 site.

Detailed Summary

Memory deficits are common after traumatic brain injuries (TBI) and are characteristic of various forms of dementia, such as Alzheimer's disease and its common precursor mild cognitive impairment (MCI). This project intends to assess the efficacy of cognitive rehabilitation in these patient populations. We will also use neuroimaging (functional magnetic resonance imaging - fMRI) to assess changes in brain activity that occur following cognitive rehabilitation.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsMild Cognitive Impairment, Alzheimer's Disease, Traumatic Brain Injury
CountriesUnited States
CollaboratorsEmory University

Timeline

Phase 1CompletedFinished
20082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedJul 14, 2008
Enrollment StartJul 1, 2008
Primary CompletionSep 1, 2014
TodayJul 2, 2026
Enrollment to primary: 6.2 yearsPosted 18.0 years ago

Interventions

Mnemonic strategy training (MST)behavioral

Repeated exposure (XP)behavioral

Subtracting Cues trainingbehavioral