At a glance
ClinicalIndex Comparison RecordN/ACompleted· 32 enrolled
Drug / intervention
Sevoflurane group +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Addition of Nitrous Oxide to a Sevoflurane or Propofol Based Anesthetic and Its Effects on Depth of Anesthesia Indices (N20)
In Brief
A clinical study evaluating Sevoflurane group and Propofol group for Deep Sedation and Anesthesia, General. Completed, enrolled 32 participants across 1 site.
Detailed Summary
The study hypothesizes that adding 60% nitrous oxide to a steady state sevoflurance or propofol anesthetic will lead to a decrease in both BIS and Entropy indices during a constant level of surgical stimulus
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsDeep Sedation, Anesthesia, General
CountriesUnited States
Collaborators--
Timeline
N/ACompletedFinished
20082009201020112012201320142015201620172018201920202021202220232024202520262027
Enrollment StartMar 2008
First PostedJul 2008
Primary CompletionOct 2010
TodayJul 2026
First PostedJul 17, 2008
Enrollment StartMar 1, 2008
Primary CompletionOct 1, 2010
TodayJul 2, 2026
Enrollment to primary: 2.6 yearsPosted 18.0 years ago
Interventions
Sevoflurane groupdrug
Addition of 60% nitrous oxide for 20 minutes duration, then back to 1:1 oxygen/air mixture.
Propofol groupdrug
Addition of 60% nitrous oxide for 20 minutes duration, then back to 1:1 oxygen/air mixture.