CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 616 enrolled
Drug / intervention
Teicoplanin +1 moredrug
Likely dose
Teicoplanin 10mg/kgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00719056
NCT00719056Phase 4Completed
CompareCT.gov

Efficacy of Teicoplanin for the Prevention of Surgical Site Infections After Total Hip or Knee Arthroplasty: A Prospective, Open-Label Randomized Study

University of Athens·interventional·Posted Jul 21, 2008·Updated Jul 21, 2008

In Brief

A Phase 4 clinical trial evaluating Teicoplanin and β-lactams or ciprofloxacin for Total Hip and Knee Arthroplasties. Completed, enrolled 616 participants across 3 sites.

Detailed Summary

This is a prospective, open-label, randomized clinical trial where patients were administered prophylaxis for total hip or knee arthroplasty either with teicoplanin or with other antibiotics. The study is aiming to evaluate any differences between these two different strategies of antimicrobial prophylaxis in the occurrence of surgical site infections

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsTotal Hip and Knee Arthroplasties
CountriesGreece
CollaboratorsKAT Hospital of Athens

Timeline

Phase 4CompletedFinished
200420052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedJul 21, 2008
Enrollment StartAug 1, 2004
Primary CompletionDec 1, 2005
Study CompletionDec 1, 2007
TodayJul 2, 2026
Enrollment to primary: 1.3 yearsPosted 17.9 years ago

Interventions

Teicoplanindrug

The selected dose was 10mg/kg and it was given intravenously by a catheter inserted under aseptic conditions in a forearm vein within 15 minutes; it was diluted in one 5% glucose solution of a 50 ml final volume

β-lactams or ciprofloxacindrug

Multiple doses for up to six consecutive days